What’s the Best Treatment for Dry Mouth? Pharmacist Explains
- Samer Altameemi
- Jun 1
- 2 min read
Updated: Jun 5

By Samer Altameemi- RPh (affiliate disclosure below)
Dry mouth, also called xerostomia, occurs when the mouth does not produce enough saliva. It can be caused by medications, dehydration, mouth breathing, aging, medical conditions, or treatments such as radiation therapy.
Because saliva helps protect the teeth, gums, and oral tissues, treating dry mouth is about more than comfort—it’s also important for oral health.
From a pharmacist’s perspective, the best treatment depends on the cause and severity of symptoms.
Stay Hydrated First
One of the simplest treatments is increasing fluid intake throughout the day.
Drink water regularly, especially:
During exercise
In hot weather
When taking medications that may cause dry mouth
Small, frequent sips are often more helpful than drinking large amounts at once.
Saliva Substitute Sprays
Use Biotène Dry Mouth Oral Rinse, Biotène Moisturizing Spray, or similar saliva substitutes to help lubricate the mouth temporarily.
These products may help:
Relieve dryness
Improve comfort while speaking
Make swallowing easier
They are often most useful at bedtime or during long periods of talking.
Dry Mouth Lozenges and Melts
Use XyliMelts® , ACT® Dry Mouth, or Biotène Lozenges to provide longer-lasting moisture.
These products slowly dissolve and help:
Stimulate saliva production
Reduce nighttime dry mouth
Improve oral comfort
Xylitol-containing products may also help protect against cavities.
Sugar-Free Gum
Chewing sugar-free gum containing xylitol may stimulate the body’s natural saliva production. This is often one of the most effective options for people who still have some salivary gland function.
It may be especially helpful:
After meals
During the day
For medication-related dry mouth
Mouth Rinses for Dry Mouth
Use Biotène Dry Mouth Oral Rinse instead of alcohol-containing mouthwashes.
Alcohol-based mouthwashes may worsen dryness, while dry-mouth rinses are designed to moisturize and protect oral tissues.
Check Your Medications
One of the most common causes of dry mouth is medication.
Common examples include:
Antihistamines for allergies.
Sleep aids containing diphenhydramine
Antidepressants
Some blood pressure medications
Bladder contol medications
If dry mouth began after starting a medication, speak with your healthcare provider or pharmacist.
Found OTC is your place to find smart over-the-counter solutions for common daily conditions, designed by the pharmacist.

Pharmacist Reviewed: the information in this article was clinically reviewed by Samer Altameemi, a licensed pharmacist. It is intended for educational purposes, not to substitute for a doctor's professional medical advice.
Disclosure: some links in the above article are affiliate links where we might earn a small commission at no extra cost to you.





