Runny Nose
Over the counter relief options
Nasal congestion occurs when allergens or irritants trigger inflammation inside the nasal lining, causing the blood vessels to swell and the tissues to become blocked. This swelling narrows the nasal passages, making it difficult to breathe. Nasal steroid sprays help by entering the nasal cells and blocking the release of inflammatory chemicals shrinking swollen tissues over time. Antihistamines can reduce congestion linked to histamine release, while saline sprays and rinses physically clear mucus and allergens to improve airflow.
Pharmacist-recommended products​​
Please be advised that if you buy something through these links, we may earn an affiliate commission at no additional cost to you
​​​​​​​
Antihistamine Nasal Sprays
Azelastine (Astepro®)
A fast-acting antihistamine spray that relieves itching, sneezing, runny nose, and nasal irritation within minutes. It works directly on nasal histamine receptors, making it ideal for sudden allergy flare-ups or breakthrough symptoms when oral antihistamines are not enough. Best for short-term or as-needed use, as some users may notice a bitter taste or mild drowsiness.
​
Nasal Decongestant Sprays (Short-Term Relief)
Xylometazoline (Sinex®)
A very fast-acting decongestant spray that shrinks swollen nasal tissues within minutes for smooth airflow. Its effect lasts several hours, making it helpful before important daytime activities. Because it constricts blood vessels strongly, it must be limited to 3 days of use to avoid rebound congestion.
​
Oxymetazoline (Afrin®, Mucinex®)
A long-acting decongestant providing up to 12 hours of relief. Frequently used at night for people who cannot breathe well when lying down. Works longer than xylometazoline but still cannot be used for more than 3 consecutive days.
​
Phenylephrine Nasal Drops
A short-acting option that provides quick but brief decongestion. Drops allow more precise dosing, especially for children or people who struggle with sprays. However, it still must be limited to 3 days to prevent rebound effects.
​​​
Steroid Nasal Sprays (Long-Term Management)
Fluticasone (Flonase®)
The strongest OTC steroid, making it ideal for moderate to severe congestion and multi-symptom allergies (itching, sneezing, runny nose, and even some eye symptoms). Available in standard and Sensimist®versions, with scented or unscented options. Best for people who need broad, all-day allergy control.
​
Mometasone (Nasonex®)
Provides high potency with a gentler, low-irritation feel, making it great for sensitive noses or people who dislike scented sprays. Well suited for long-term daily use, especially for year-round allergies.
​
Triamcinolone (Nasacort®)
Offers moderate strength and a lighter, alcohol-free, fragrance-free formulation. Best for mild to moderate allergies, individuals who prefer a softer spray, or those who want to avoid drying sensations.
​
Non-Medicated Relief
Saline Nasal Rinses
Rinse out allergens, dust, mucus, and irritants while moisturizing the nasal lining. Useful for people with dry noses, pregnant users, high blood pressure, or anyone avoiding medication. Safe for daily or multiple-times-per-day use.
​
Nasal Inhaler Sticks
Contain menthol, eucalyptus, or camphor to create a cooling sensation that temporarily improves airflow. They help with the sensation of stuffiness but do not treat inflammation or congestion. Best for short-term comfort, travel, or quick refreshment.
View on Amazon​​
​
-
For quick short-term relief, decongestant sprays like oxymetazoline, xylometazoline, or phenylephrine work very fast and are the fastest options for sudden congestion. However, they should not be used for more than 3 days to avoid rebound congestion. Azelastine also provides rapid relief from sudden allergy flares but is best for short-term use only, not daily long-term control.
-
For seasonal or ongoing allergies, steroid nasal sprays such as fluticasone, mometasone, or triamcinolone are the safest and most effective when used daily and consistently. Among these, fluticasone offers the strongest long-term control, mometasone provides gentle but powerful relief for sensitive noses, and triamcinolone is the lightest steroid option, ideal for mild to moderate symptoms.
-
If you prefer non-medicated options, saline sprays or nasal rinses offer excellent drug-free daily relief, helping flush out allergens and moisturize dry nasal passages. Menthol inhaler sticks provide a cooling sensation only, offering quick but temporary comfort without treating inflammation or congestion.
-
For overnight breathing, oxymetazoline is often preferred because it provides up to 12 hours of relief, making it easier to breathe while lying down.
-
Avoid using steroid sprays during active nasal infections, and seek medical advice if symptoms continue longer than 1–2 weeks, worsen over time, or are accompanied by fever, severe facial pain, or persistent blockage.
​
You may also want to visit:
​